Prof. Debasish Hota

Prof. Debasish Hota

Professor & Head
Pharmacology

pharm_debasish@aiimsbhubaneswar.edu.in

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Prof. Debasish Hota

Professor & Head

Pharmacology

Degree / Diploma Name of the University/ Institution Subject Year of Passing
MBBS 1986 Maharaja Krishna Chandra Gajapati Medical College & Hospital, Berhampur University (Odisha)
MD 1994 Pharmacology IMS, BHU, Varanasi
DM 1997 Clinical Pharmacology Postgraduate Institute of Medical Education and Research, Chandigarh

  1. Hota D, Acharya SB. Studies on peripheral actions of isatin. Indian Journal of Experimental Biology 1994; 32: 710-717.
  2. Hota D, Tandan R, Bhattacharya SK. Supportive management and terminal care in cancer patients. Journal of Internal Medicine (India) 1995 (Suppl. 9): 27-29.
  3. Bhaduri J, Hota D, Acharya SB. Role of prostaglandin synthesis inhibitors on chemically Induced seizures. Indian Journal of Experimental Biology 1995; 33: 477-481.
  4. Ganguli S, Hota D, Goel RK, Acharya SB, Bhattacharya SK. Neuro-pharmacological Studies on Fusarium toxins-I: Total toxin extracts from Fusarium moniliforme. Indian Journal of Experimental Biology 1996; 34: 408-417.
  5. Ganguli S, Hota D, Goel RK, Acharya SB, Bhattacharya SK. Neuro-pharmacological studies on Fusarium toxins-II: Total toxin extracts from Fusarium oxysporum. Indian Journal of Experimental Biology 1996; 34: 418-426.
  6. Ganguli S, Hota D, Goel RK, Acharya SB, Bhattacharya SK. Neuro-pharmacological studies on Fusarium toxins-III: Neurochemical investigations on total toxin extracts from Fusarium moniliforme and Fusarium oxysporum. Indian Journal of Experimental Biology 1996; 34:531-534
  7. Hota D, James H, Bhargava VK. Treatment of Bronchial Asthma; Drugs Bulletin (PGIMER, Chandigarh, India) 1996; 20(3) 27-37.
  8. Hota D, James H, Bhargava VK. Pharmacotherapy of gastro oesophageal reflux disease. Bulletin PGIMER; (Chandigarh, India) 1998; 32: 51-57.
  9. Jhaj R, Goel NK, Gautam CS, Hota D, Sangeeta B, Sood A, Sachdev A. Prescribing patterns and cost of antihypertensive drugs in an internal medicine clinic. Indian Heart Journal; 2001; 53:323-7.
  10. Vasudev K, Hota D. Patient Compliance: the cornerstone of successful therapeutics. J Indian Med Assoc 2002; 50:803-806.
  11. Kumar V, Kumar S, Sahni JK, Hota D. Migratory orofacial swelling: A   rare form of Melkersson-Rosenthal Syndrome. Indian J Otology 2002; 8:78-80.
  12. Anuradha K, Hota D, Pandhi P. Pharmacotherapy of osteoporosis. Drugs Bulletin (PGIMER, Chandigarh, India). 2002; 26:12-29.
  13. Sharma PK, Hota D & Pandhi P. COX-2 inhibitors. A new class of NSAIDs. Drugs Bulletin (PGIMER, Chandigarh, India). 2002;26: 40-57.
  14. Sukhija M, Hota D. Pharmacotherapy of Urinary Tract Infections. Drugs Bulletin (PGIMER, Chandigarh, India) 2003;27:34-48.
  15. Yanpallewar SU, Hota D, Rai S, Kumar M, Acharya SB. Nimodipine attenuates biochemical, behavioral and histopathological alterations induced by acute transient and long-term bilateral common carotid occlusion in rats. Pharmacol Res. 2004;49:143-50
  16. Anuradha K, Hota D, Pandhi P. Possible mechanisms of insulin antinociception. Methods Find Exp Clin Pharmacol. 2004;26 :5-8.
  17. Anuradha K, Hota D, Pandhi P. Investigation of central mechanism of insulin induced hypoglycemic convulsions in mice. Indian J Exp Biol. 2004; 42 :368-72.
  18. Sukriti, Hota D & Pandhi P: Effect of Nimodipine in formalin induced orofacial dyskinesia in rat. Methods Find Exp Clin Pharmacol. 2004;26:253-6.
  19. Sharma PK, Hota D, Pandhi P. Biologics in rheumatoid arthritis. J Assoc Physicians India. 2004; 52:231-236.
  20. Dhawan S, Singh B, Garg SK, Hota D, Dash RJ, Singla AK, Sinha VR. Bioavailability of immediate and extended-release formulations of glipizide in healthy male volunteers. Clin Pharmacokinet. 2006; 45:317-24.
  21. Pattanaik S, Hota D, Prabhakar S, Kharbanda P, Pandhi P. Effect of piperine on the steady-state pharmacokinetics of phenytoin in patients with epilepsy. Phytother Res 2006 ;20 : 683-686.
  22. Shitak R, Sahai AK, Hota D, Chakrabarti A. Antiseizure efficacy of nimodipine in pentylenetetrazole and kainic acid combined seizure models in mice. Indian J Physiol Pharmacol 2006; 50: 265-272.
  23. Jose V, Hota D, Bhansali A, Pandhi P. Randomised Double Blind Study Comparing The Efficacy and Safety of Lamotrigine versus Amitriptyline in painful diabetic neuropathy. Diabet Med 2007; 24:377-383.
  24. Shitak R, Sahai AK, Hota D, Chakrabarti A. Evaluation of the modulatory role of nimodipine in seizures induced by kainic acid and pentylenetetrazole in mice. Methods Find Exp Clin Pharmacol. 2007; 29 :11-17.
  25. Hota D, Bansal V, Pattanaik S. Evaluation of Ketamine, Nimodipine, Gabapentin and Imipramine in Partial Sciatic Nerve Transection Model of Neuropathic Pain in Rat: An Experimental Study. Methods Find Exp Clin Pharmacol 2007, 29: 443-446.
  26. Jose VM, Sharma N, Hota D, Pandhi P. Changing chronobiology of cardiovascular outcome following prophylaxis. Nepal Med Coll J. 2007;9:1-5.
  27. Jose VM, Bhalla A, Sharma N, Hota D, Shivaprasad S, Pandhi P. Study of association between use of complementary and alternative medicine and non-compliance with modern medicine in patients presenting to the emergency department. J Postgrad Med. 2007;53:96-101.
  28. Mittal N, Hota D. Urinary incontinence. Drugs Bulletin (PGIMER, Chandigarh, India) 2007;31:1-16.
  29. Mittal N, Joshi R, Hota D, Chakrabarti A. Evaluation of antihyperalgesic effect of curcumin on formalin-induced orofacial pain in rat. Phytother Res 2009; 23: 507-512.
  30. Pattanaik S, Hota D, Prabhakar S, Kharbanda P, Pandhi P. Pharmacokinetic interaction of single dose of piperine with steady-state carbamazepine in epilepsy patients. Phytother Res. 2009 Sep;23(9):1281-1286
  31. Bansal D, Bhansali A, Hota D, Chakrabarti A, Dutta P. Amitriptyline or Pregabalin in diabetic painful neuropathy: A Randomised double-blind placebo controlled trial. Diabet Med 2009. 2009;26:1019-1026.
  32. Singh S, Hota D, Prakash A, Khanduja KL, Arora SK, Chakrabarti A. Allo-pregnanolone, the active metabolite of progesterone protects against neuronaldamage in picrotoxin-induced seizure model in mice. Pharmacol Biochem Behav 2010;94:416-422. Epub 2009 Oct 17.
  33. Kumar G, Hota D, Nahar Saikia U, Pandhi P. Evaluation of Analgesic Efficacy, Gastrotoxicity and Nephrotoxicity of Fixed Dose Combinations of Nonselective, Preferential and Selective Cyclooxgenase Inhibitors with Paracetamol in Rats. Exp Toxicol Pathol 2010 ;62:653-62. Epub 2009 Oct 2.
  34. Bansal D, Hota D, Chakrabarti A. research methodological issues in evaluating herbal interventions. Open access Journal of Clinical trials 2010; 11 Feb.
  35. Mittal R, Mittal N, Hota D, Ahluwalia J, Suri V, Aggarwal N, Chakrabarti A. A randomised, double blind, placebo controlled study to evaluate the effect of isoflavones on ADP and epinephrine induced platelet aggregation in oophorectomised women. Pharmacologyonline 2010;1: 458-468.
  36. Kaur H, Hota D, Bhansali A, Dutta P, Bansal D, Chakrabarti A. A comparative trial to evaluate Amitriptyline and Duloxetine in painful diabetic neuropathy: a randomized, double-blind, cross-over clinical trial. Diabetes Care 2011. 2011;34:818-822.
  37. Mittal N, Hota D, Dutta P, Bhansali A, Suri V, Aggarwal N, Marwah RK,  Evaluation of isoflavone effect on thyroid economy and autoimmunity in oophorectomised women: a randomised, double-blind, placebo-controlled trial. Indian J Med Res. 2011;133:633-640.
  38. Sood N, Hota D, Sahai AK, Chakrabarti A. Nicotine Reversal of Anticonvulsant Action of Topiramate in Kainic Acid-Induced Seizure Model in Mice. Nicotine Tob Res 2011;13:1084-1091.
  39. Dhamija P, Bansal D, Srinivasan A, Bhalla A, Hota D, Chakrabarti A. Patterns of prescription drug use and incidence of drug-drug interactions in patients reporting to medical emergency. Fundam Clin Pharmacol. 2013;27: 231-237.
  40. Saha L, Hota D, Chakrabarti A. Evaluation of lercanidipine in Paclitaxel-induced neuropathic pain model in rat: a preliminary study. Pain Res Treat. 2012;2012:143579.
  41. Singh PK, Hota D, Dutta P, Sachdeva N, Chakrabarti A, Srinivasan A, Singh I, Bhansali A. Pantoprazole improves glycemic control in type 2 diabetes: a randomized, double-blind, placebo-controlled trial. J Clin Endocrinol Metab. 2012 Nov;97(11):E2105-E2108.
  42. Hota D, Rajagopalan S, ChakrabartiA, Batra YK. Emerging targets and Drugs in Pharmacotherapy of acute Pain. Indian J Pain 2012; 26: 99-102.
  43. Sondekoppam RV, Hota D, Batra YK. Update on interventional management of Primary Headache disorders. Indian J Pain 2012; 26: 144-146.
  44. Mohapatra PR, Hota D. Dietary fortification of aspirin: a novel modality for cancer prevention. Am J Med. 2013 Feb;126(2):e13. doi: 10.1016/j.amjmed.2012.06.035.
  45. Singh I, Rajagopalan S, Srinivasan A, Achuthan S, Dhamija P, Hota D, Chakrabarti A. Preoperative statin therapy is associated with lower requirement of renal replacement therapy in patients undergoing cardiac surgery: a meta-analysis of observational studies. Interact Cardiovasc Thorac Surg. 2013;17:345-352.
  46. Srinivasan A, Syal K, Banerjee D, Hota D, Gupta D, Kaul D, Chakrabarti A. Low plasma levels of cholecalciferol and 13-cis retinoic acid in tuberculosis – Implications in the host based chemotherapy. Nutrition. 2013; 29: 1245-1251.
  47. Dhamija P, Hota D, Kochhar R, Sachdev A, Chakrabarti A. Randomized clinical trial: Atorvastatin versus placebo patients with acute exacerbation of mild to moderate ulcerative colitis. Indian J Gastroenterol. 2013 Nov 13PubMed PMID: 24222372.
  48. Rudroju N, Bansal D, Talakokkula ST, Gudala K, Hota D, Bhansali A, Ghai B. Comparative efficacy and safety of six antidepressants and anticonvulsants in painful diabetic neuropathy: a network meta-analysis. Pain Physician. 2013 Nov-Dec;16(6):E705-14.
  49. Kumar S, Bansal D, Hota D, Jain M, Singh PK, BL Pandey BL. Assessment of clinical outcomes and prescribing behaviour among inpatients with severe preeclampsia and eclampsia: An Indian experience. Indian Journal of Pharmacology 2014; 46 (1). To be published in Feb 2014 Issue.
  50. Mittal R, Mittal N, Hota D, Suri V, Aggarwal N, Chakrabarti A. Antioxidant effect of isoflavones: A randomized, double-blind, placebo controlled study in oophorectomized women. Int J Appl Basic Med Res 2014, Vol 4, Issue 1.
  51. Singh I, Achuthan S, Chakrabarti A, Rajagopalan S, Srinivasan A, Hota D. Influence of pre-operative use of serotonergic antidepressants (SADs) on the risk of bleeding in patients undergoing different surgical interventions: a meta-analysis. Pharmacoepidemiol Drug Saf. 2014 Apr 30. doi: 10.1002/pds.3632.[Epub ahead of print] PubMed PMID: 24789076.
  52. Ghai B, Bansal D, Hota D, Shah CS. Off-label, low-dose naltrexone for refractory chronic low back pain. Pain Med. 2014 May;15(5):883-4. PubMed PMID: 24967470.
  53. Achuthan S, Singh I, Varthya SB, Srinivasan A, Chakrabarti A, Hota D. Gabapentin prophylaxis for postoperative nausea and vomiting in abdominal surgeries: a quantitative analysis of evidence from randomized controlled clinical trials. Br J Anaesth. 2015 Jan 8. pii: aeu449. [Epub ahead of print] Review. PubMed PMID: 25571932.
  54. Thangaraju P, Chakrabarti A, Banerjee D, Hota D, Tamilselvan, Bhatia A, Gupta A. Dual blockade of Renin Angiotensin system in reducing the early changes of diabetic retinopathy and nephropathy in a diabetic rat model. N Am J Med Sci. 2014 Dec;6(12):625-32. doi: 10.4103/1947-2714.147978. PubMed PMID: 25599050; PubMed Central PMCID: PMC4290051.
  55. Rajagopalan S, Dutta P, Hota D, Bhansali A, Srinivasan A, Chakrabarti A. Effect of low dose pioglitazone on glycemic control and insulin resistance in Type 2 diabetes: A randomized, double blind, clinical trial. Diabetes Res Clin Pract 2015;109:e32-35.
  56. Maiti R, Bhatia V, Padhy BM, Hota D. Essential medicines: An Indian perspective. Indian J Community Med 2015;40:223-32.
  57. Chakrabarti A, Shivabasappa S, Hota D, Saikia UN. Lercanidipine alleviates hyperalgesia and allodynia in Rodent Model of paclitaxel induced neuropathy. Journal of the Neurological Sciences 357, e358.
  58. Hota D, Srinivasan A, Dutta P, Bhansali A, Chakrabarti A. Off-Label, Low-Dose Naltrexone for Refractory Painful Diabetic Neuropathy. Pain Medicine 2015; 0: 1–2. doi: 10.1093/pm/pnv009
  59. Maiti R, Sirka CS, Shaju N, Hota D. Halometasone monohydrate (0.05%) in occupational contact dermatitis. Indian J Pharmacol. 2016 Mar-Apr;48(2):128-33.
  60. Maiti R, Mishra BR, Hota D. Effect of High-Frequency Transcranial Magnetic Stimulation on Craving in Substance Use Disorder: A Meta-Analysis. J Neuropsychiatry Clin Neurosci. 2017 Spring;29(2):160-171.
  61. Maiti R, Mukherjee S, Hota D. Recurrence Rate and Graft Stability With Fibrin Glue Compared With Suture and Autologous Blood Coagulum for Conjunctival Autograft Adherence in Pterygium Surgery: A Meta-Analysis. Cornea. 2017 Oct;36(10):1285-1294.
  62. Maiti R, Sirka CS, Ashique Rahman MA, Srinivasan A, Parida S, Hota D. Efficacy and Safety of Tazarotene 0.1% Plus Clindamycin 1% Gel Versus Adapalene 0.1% Plus Clindamycin 1% Gel in Facial Acne Vulgaris: A Randomized, Controlled Clinical Trial. Clin Drug Investig. 2017 Nov;37(11):1083-1091.
  63. Gupta P, Rai A, Mukherjee KK, Sachdeva N, Radotra BD, Punia RPS, Vashista RK, Hota D, Srinivasan A, Dhandapani S, Gupta SK, Bhansali A, Dutta P. Imatinib Inhibits GH Secretion From Somatotropinomas. Front Endocrinol (Lausanne). 2018 Aug 27;9:453.
  64. Tripathy SK, Rao PB, Nanda SN, Nayak C, Samal BP, Jain M, Srinivasan A, Hota D. Safety and efficacy of epsilon aminocaproic acid (EACA) as an antihemorrhagic drug in bilateral one stage total knee arthroplasty: A double-blind randomized controlled trial. Knee. 2020 Jan;27(1):229-234.
  65. Behera KK, Saharia GK, Hota D, Sahoo DP, Sethy M, Srinivasan A. Effect of Vitamin D Supplementation on Thyroid Autoimmunity among Subjects of Autoimmune Thyroid Disease in a Coastal Province of India: A Randomized Open-label Trial. Niger Med J. 2020 Sep-Oct;61(5):237-240.
  66. Hota D, Srinivasan A, Sahoo JP, Behera KK, Patro BK, Bandyopadhyay D, et al. (2020) Possible Anti-Diabetic and Anti-Hyperlipidemic Efficacy of Blended Rice Bran Oil with Sesame Oil in Comparison with Soybean Oil: A Clinical Investigation in Pre-Diabetic and Diabetic Individuals. J Clin Trials 10: 419.
  67. Behera KK, Hota D, Mahapatra A. COVID 19 and diabetes: An endocrinologist’s perspective. J Family Med Prim Care. 2020 Sep 30;9(9):4512-4515.
  68. Behera KK, Begum J, Hota DMosaicism Triple X Syndrome in a Young Woman Presenting as Primary Amenorrhea with Short Stature.JCR 2021;11:5-7
  69. Srinivasan A, Dutta P, Bansal D, Chakrabarti A, Bhansali AK, Hota D. Efficacy and safety of low-dose naltrexone in painful diabetic neuropathy: A randomized, double-blind, active-control, crossover clinical trial. J Diabetes. 2021 Oct;13(10):770-778.
  70. Sethuramalingam S, Maiti R, Hota D, Srinivasan A. Effect of Colchicine in Reducing Inflammatory Biomarkers and Cardiovascular Risk in Coronary Artery Disease: A Meta-analysis of Clinical Trials. Am J Ther. 2023 May 1;30(3):e197-e208.
  71. Ramasubbu MK, Maji S, Padhan M, Maiti R, Hota D, Majumdar SKD, Srinivasan A. Chemotherapy-induced hand foot syndrome: comparative efficacy and safety of pharmacological prophylaxis – systematic review and Bayesian network meta-analysis. BMJ Support Palliat Care. 2022 Dec 23:spcare-2022-004011.
  72. Singh M, Mehendale S, Guleria R, Sarin R, Tripathy S, Gangakhedkar RR, Katoch K, Pandey RM, Panda S, Pati S, Mohapatra PR, Joshi S, Narasimhaiah S, Kodan P, Bhaskar S, Rani R, Khan AM, Swaminathan S; PreVenTB Trial Team. PreVenTB trial: protocol for evaluation of efficacy and safety of two vaccines VPM1002 and Immuvac (Mw) in preventing tuberculosis (TB) in healthy household contacts of newly diagnosed sputum smear-positive pulmonary TB patients: phase III, randomised, double-blind, three-arm placebo-controlled trial. BMJ Open. 2024 Aug 31;14(8):e082916.
  73. Mishra A, Jena SK, Srinivasan A, Tripathy A, Maiti R, Hota D. Effect of an Add-On Multi-Strain Probiotic Formulation in the Prevention of Recurrent Urinary Tract Infections: A Double-Blind Randomized Placebo-Controlled Trial. Microbiology Research. 2024; 15(4):2330-2340.
  74. Hota D, Srinivasan A, Panigrahi MK, Dalua SS, Tiwari P, Valavan R. A clinical study on the efficacy and safety of poly-herbal formulation in managing functional dyspepsia. Phytomedicine Plus: 5 (1). 2025: 100671.
  75. Ramasubbu MK, Hota D, Das Majumdar SK, Parida DK, Mukherjee P, Srinivasan A. A group sequential response-adaptive randomized double-blinded clinical trial to evaluate the safety and efficacy of add-on olanzapine plus pregabalin for the prevention of chemotherapy-induced nausea and vomiting. Support Care Cancer. 2025 Feb 19;33(3):203.
  76. Mishra A, Mishra BR, Mohapatra D, Srinivasan A, Maiti R, Hota D. Carbamazepine toxicity with concomitant levetiracetam therapy in patients with epilepsy. Int J Neurosci. 2025 Apr 10:1-7.
Prof. Debasish Hota

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